ROC Website Shutdown

Attention: The ROC website will be going permanently offline by June 21, 2019. Please contact rochelp@uwctc.org if you believe you need continued access to the site. Thank you!

Current Studies



(Epidemiologic registry)

The primary goal of the Epistry Database working group is to develop the rationale and methods for a standard reliable and valid Epidemiologic databank of out of hospital cardiac arrest and life threatening trauma cases with in-hospital outcomes after 5 years enabling the identification of best practices via observational study and mega trials with the ultimate goal of improving resuscitation success defined as survival to hospital discharge rates across ROC centers.



(Prehospital Tranexamic Acid Use for Traumatic Brain Injury)

This multi-center, Phase II trial is designed to determine if Tranexamic Acid (TXA) initiated in the prehospital setting improves long-term neurologic outcome compared to placebo in patients with moderate to severe TBI who are not in shock. 

The primary null hypothesis is that the proportion of patients who have a favorable neurologic outcome (GOS-E > 4) at six months post injury who are randomly assigned to TXA is not different from the proportion of patients who have have a favorable neurologic outcome who are randomly assigned to placebo.
Evaluated secondary outcomes will include intracranial hemorrhage progression, frequency of neurosurgical interventions, 28-day survival, ICU-free and hospital-free days.
Evaluated tertiary outcomes will include seizures, cerebral ischemic events, MI, DVT, and PE post randomization through 28 days or hospital discharge whichever occurs first.

More information is available at website: www.ClinicalTrials.gov   Enter study ID: NCT01990768